Download Clinical Proteomics: Methods and Protocols by Young-Ki Paik, Hoguen Kim, Eun-Young Lee, Min-Seok Kwon, PDF

By Young-Ki Paik, Hoguen Kim, Eun-Young Lee, Min-Seok Kwon, Sang Yun Cho (auth.), Antonia Vlahou (eds.)

The box of medical proteomics has quickly advanced in the past few years and is consistently growing to be as new methodologies and applied sciences emerge. In Clinical Proteomics, a choose staff of best researchers has contributed their cutting-edge methodologies on protein profiling and id of sickness biomarkers in tissues, microdissected cells and physique fluids. Experimental ways concerning the appliance of two-dimensional electrophoresis, multi-dimensional liquid chromatography, SELDI/MALDI mass spectrometry and protein arrays, in addition to the bioinformatic and statistical instruments pertinent to the research of proteomics info, are completely distinct in those easily reproducible tools and protocols, defined throughout the step by step tutorial layout of the hugely profitable Methods in Molecular Biology™ series.

With its multi-disciplinary technique, Clinical Proteomics provides built-in, state-of-the-art options absolute to be useful to a variety of researchers together with clinicians, molecular biologists, chemists, bioinformaticians and computational biologists.

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Koo, B. , Lee, D. , Ha, H. , Kim, J. , and Kim, C. W. (2005) Comparative analysis of the tear protein expression in blepharitis patients using two-dimensional electrophoresis. J. Proteome Res. 4, 719–724. 18. Grus, F. , Podust, V. , Dalmasso, E. , and Pfeiffer, N. (2005) SELDI-TOF-MS ProteinChip array profiling of tears from patients with dry eye. Invest. Ophthalmol. Vis. Sci. 46, 863–876. 19. Amado, F. , Vitorino, R. , Domingues, P. , Lobo, M. , and Duarte, J. A. (2005) Analysis of the human saliva proteome.

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2005) Proteomic profiling of human pleural effusion using two-dimensional nano liquid chromatography tandem mass spectrometry. J. Proteome Res. 4, 1274–1286. Khalil, A. A. and James, P. (2007) Biomarker discovery: a proteomic approach for brain cancer profiling. Cancer Sci. 98, 201–213. Khodavirdi, A. , Nelson, P. , and Roy-Burman, P. (2006) Increased expression of osteopontin contributes to the progression of prostate cancer. Cancer Res. 66, 883–888. Vincourt, J. , and Magdalou, J. (2006) Establishment of a reliable method for direct proteome characterization of human articular cartilage.

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