By Dan M. Roden
This entire and concise presentation of genetic elements in heart problems and their reaction to treatment consolidates wisdom of this high-interest and rising subject. masking huge components of up to date genomic medication and particular cardiovascular ailments, this e-book is a needs to for someone looking to greater comprehend this quickly constructing box.
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Additional info for Cardiovascular Genetics and Genomics (American Heart Association Clinical Series)
All these issues are inevitably related to genetic and environmental factors. The term ethnicity stems from the Greek ethnos [1,2], meaning people or nation. It is “a multi-faced quality that refers to the group to which people belong, and/or are perceived to belong, as a result of certain shared characteristics, including geographical and ancestral origins, but particularly cultural traditions and languages” . However, the concept of ethnicity in healthcare and public health remains a controversial variable, with many ethical and definition issues.
6 Cardon LR, Palmer LJ. Population stratification and spurious allelic association. Lancet 2003; 361: 598–604. 7 Pritchard JK, Stephens M, Rosenberg NA, Donnelly P. Association mapping in structured populations. Annals of Human Genetics 2000; 67: 170–181. 8 Pritchard JK, Rosenberg NA. Use of unlinked genetic markers to detect population stratification in association studies. Annals of Human Genetics 1999; 65: 220–228. 30 Part I Principles 9 Rosenberg NA, Pritchard JK, Weber JL et al. Genetic structure of human populations.
1. Optimality criteria for affected sib-pair test. Human Heredity 1994; 44: 37–43. 5 Risch N, Zhang H. Extreme discordant sib pairs for mapping quantitative trait loci in humans. Science 1995; 268: 1584–1589. 6 Cardon LR, Palmer LJ. Population stratification and spurious allelic association. Lancet 2003; 361: 598–604. 7 Pritchard JK, Stephens M, Rosenberg NA, Donnelly P. Association mapping in structured populations. Annals of Human Genetics 2000; 67: 170–181. 8 Pritchard JK, Rosenberg NA. Use of unlinked genetic markers to detect population stratification in association studies.