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By Dan M. Roden

This entire and concise presentation of genetic elements in heart problems and their reaction to treatment consolidates wisdom of this high-interest and rising subject. masking huge components of up to date genomic medication and particular cardiovascular ailments, this e-book is a needs to for someone looking to greater comprehend this quickly constructing box.

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Additional info for Cardiovascular Genetics and Genomics (American Heart Association Clinical Series)

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All these issues are inevitably related to genetic and environmental factors. The term ethnicity stems from the Greek ethnos [1,2], meaning people or nation. It is “a multi-faced quality that refers to the group to which people belong, and/or are perceived to belong, as a result of certain shared characteristics, including geographical and ancestral origins, but particularly cultural traditions and languages” [1]. However, the concept of ethnicity in healthcare and public health remains a controversial variable, with many ethical and definition issues.

6 Cardon LR, Palmer LJ. Population stratification and spurious allelic association. Lancet 2003; 361: 598–604. 7 Pritchard JK, Stephens M, Rosenberg NA, Donnelly P. Association mapping in structured populations. Annals of Human Genetics 2000; 67: 170–181. 8 Pritchard JK, Rosenberg NA. Use of unlinked genetic markers to detect population stratification in association studies. Annals of Human Genetics 1999; 65: 220–228. 30 Part I Principles 9 Rosenberg NA, Pritchard JK, Weber JL et al. Genetic structure of human populations.

1. Optimality criteria for affected sib-pair test. Human Heredity 1994; 44: 37–43. 5 Risch N, Zhang H. Extreme discordant sib pairs for mapping quantitative trait loci in humans. Science 1995; 268: 1584–1589. 6 Cardon LR, Palmer LJ. Population stratification and spurious allelic association. Lancet 2003; 361: 598–604. 7 Pritchard JK, Stephens M, Rosenberg NA, Donnelly P. Association mapping in structured populations. Annals of Human Genetics 2000; 67: 170–181. 8 Pritchard JK, Rosenberg NA. Use of unlinked genetic markers to detect population stratification in association studies.

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